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Formulation and Characterization of Glutathione-Loaded Bioadhesive Hydrogel for Ocular Delivery-Juniper Publishers

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                                   JUNIPER PUBLISHERS-   ACADEMIC JOURNAL OF POLYMER SCIENCE Abstract Glutathione may prevent age-related, oxidative damage to ocular tissues but has poor corneal penetration. Hydrogel formulations were investigated to determine an optimized ocular delivery system. The rheology and texture profile of formulations were investigated at 25°C. The 1% w/v glutathione was incorporated into systems demonstrating desirable characteristics for ocular vehicles and physical characteristics re-determined. In vitro cumulative glutathione delivery across the bovine cornea was measured over 8 hours at 32ÂșC in Franz diffusion cells. Carbopol-containing Poloxamer systems exhibited shear-thinning behavior desirable for ocular formulations whilst Polyvinyl alcohol (PVA) and Polyacrylic acid (PAA) systems exhibited Newtonian behavior. Of the glutathione-containing ...

Energy Potential of Natural, Synthetic Polymers and Waste Materials - A Review-Juniper Publishers

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Authored by   Michael Ioelovich Abstract In this paper, the energy potential of natural (polysaccharides, lignin, etc.), and synthetic polymers (polyolefins, etc.), polymer materials (plant biomass, plastics and their solid waste), as well as combustible liquids and gases derived from them has been studied. To determine calorific values of solid, liquid and gaseous substances, various experimental and calculation methods were used. For this purpose, improved equations based on chemical structure and elemental analysis was proposed. It was shown that the conversion of solid materials into liquids or gases reduces the yield of thermal energy. Therefore for the production of thermal energy, it is more profitable to burn the solid biomass or plastic than combustible liquids and gases, derived from them. Studies have shown that lipids and lignin increase, whereas moisture and ash reduce the calorific value of biomass. The calorific value of most synthetic polymers and ...