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Synthesis of Chitosan-Co-Lactic Acid Nanoparticles and their Potential as a Carrier of Anticancer Drug

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   JUNIPER PUBLISHERS-   ACADEMIC JOURNAL OF POLYMER SCIENCE Abstract This study aims to design some medicinally important biopolymer based Nano carriers. The study undertakes synthesis, characterization of Chitosan-co-lactic acid nanoparticles and optimization of swelling ratio. The Chitosan-co-lactic acid nanoparticles were prepared by the shaking of lactic acid emulsion in Chitosan solution by emulsion crosslinking method and characterised by transmission electron microscope (TEM) analysis (size), and Fourier transform infrared spectra (FTIR) (structural) and SEM (morphology). The particles were dispersed in a phosphate buffer saline (PBS) and the swelling response of these nanoparticles was studied as a function of chemical composition, pH and temperature of swelling medium. To determine the encapsulation efficiency, a centrifugation method was applied. Also, the assessment of biocompatibility has been made on the basis of two in-vitro test which are BSA adsorption te...

Polyhydroxybutyrate (PHB) Production by Bacteria and its Application as Biodegradable Plastic in Various Industries-Juniper Publishers

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                                                                                    JUNIPER PUBLISHERS-   ACADEMIC JOURNAL OF POLYMER SCIENCE Abstract Commercially available plastics are commonly used in day to day life. The rate of accumulation of plastic in the environment is increasing day by day which becomes a major universal concern due to its less biodegradation property. Generated plastic waste is managed by incineration or landfill disposal. These processes are time -consuming and expensive. The main objective of the study involves the investigation bio-degradable polymers viz Polyhydroxybutyrate (PHB) produced by bacterial species (Alcaligenes). The stock culture of Alcaligenes species was cultured at a rate of 5% in production media containing 2.5% of sucros...