Posts

Showing posts with the label Copolymerization

Manufacturing and Evaluation of High-Quality Composites using Out-of-Autoclave Prepreg - Juniper Publishers

Image
  Academic Journal of Polymer Science - Juniper Publishers Abstract Carbon fiber-reinforced thermoset polymers have become popular in a wide variety of applications such as primary aerospace structures, sporting goods and wind energy systems. Autoclave processing has been the preferred method for fabricating high performance composites. However, the need for low-cost, high-performance composites prompted researchers and industries to develop new techniques such as vacuum aided resin transfer molding (VARTM) and vacuum-bag-only cure out-of-autoclave (OOA). Manufacturing parts with less than 1% void content, on the other hand, remains a difficulty. In the present study, the OOA technique was used to create high-quality (less than 0.25 percent void content) carbon/epoxy composites. The phases in the processing that result in good quality are described. Physical, mechanical, and fatigue properties of the manufactured composites were evaluated. Keywords:  Fiber-reinforced; Polymers...

Polymeric Materials for the Development of Dual↓Working Gastroretentive Drug Delivery Systems. A Breakthrough Approach

Image
   JUNIPER PUBLISHERS-   ACADEMIC JOURNAL OF POLYMER SCIENCE Abstract Oral route is the most convenient and widely used method of drug administration, representing about 90% of all therapies used. It displays great advantages, such as being non-invasive, easy to administer (with the consequent high patient compliance) and cost-effective. However, serious drawbacks to conventional oral dosage forms are imposed by the gastrointestinal tract. Large fluctuations in drug bioavailability are found due to the influence of physiological factors such as variations in pH, high enzymatic activity and gastric emptying. This is the reason why frequent drug administrations are required to maintain the therapeutic plasma level of the drug. Gastroretentive Drug Delivery Systems (GRDDS) have emerged as an ideal approach to overcome these drawbacks. They are designed to prolong the gastric residence time (GRT) of the dosage forms in the stomach so that the time between dose administration ...

Synthesis of Chitosan-Co-Lactic Acid Nanoparticles and their Potential as a Carrier of Anticancer Drug

Image
   JUNIPER PUBLISHERS-   ACADEMIC JOURNAL OF POLYMER SCIENCE Abstract This study aims to design some medicinally important biopolymer based Nano carriers. The study undertakes synthesis, characterization of Chitosan-co-lactic acid nanoparticles and optimization of swelling ratio. The Chitosan-co-lactic acid nanoparticles were prepared by the shaking of lactic acid emulsion in Chitosan solution by emulsion crosslinking method and characterised by transmission electron microscope (TEM) analysis (size), and Fourier transform infrared spectra (FTIR) (structural) and SEM (morphology). The particles were dispersed in a phosphate buffer saline (PBS) and the swelling response of these nanoparticles was studied as a function of chemical composition, pH and temperature of swelling medium. To determine the encapsulation efficiency, a centrifugation method was applied. Also, the assessment of biocompatibility has been made on the basis of two in-vitro test which are BSA adsorption te...