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Showing posts with the label Biomaterials

Polymer Composite Materials from Current Status to Future Prospects

  Abstract A call for novel material, new ideas, applications, and techniques are still and will be challenging all the time. The increased development of science and modern technology allows one to use a high-throughput search for novel materials that could give positive feedback in different areas of life. With increasing demand for high performance materials, the focus of recent researches has been to produce products with enhanced properties at minimal changes in the equipment, process and cost of inputs. The addition of clay minerals or nano-metal oxides to the polymers is to improve the polymer properties, their wide and demand characteristics or desired potential applications by producing the polymer nanocomposites. Scanning and transmission electron microscopy have led to a deeper understanding of polymer nanocomposites, a better account surface topology, structure and morphology. Read more about this article:  https://juniperpublishers.com/ajop/AJOP.MS.ID.555626.php R...

Gellan Gum Immobilized Anticancer Drugs and Gold Nanoparticles in Nanomedicine

Abstract This review is devoted to recent progress in the design of anticancer drug delivery systems with participation of unique polysaccharide gellan gum. At first a brief literature survey on conformational and phase behavior of gellan gum as a function of external stimuli, such as temperature, pH, salt addition etc. is presented. Then the immobilization protocol of anticancer drugs and gold nanoparticles within gellan-based hydrogel matrix is discussed. Release of anticancer drugs from gellan gel matrix to outer solution is considered. Cytotoxicity of gellan gum-immobilized gold nanoparticles together with their anticancer activity is summarized. Read more about this article:  https://juniperpublishers.com/ajop/AJOP.MS.ID.555588.php Read more Juniper Publishers Google Scholar articles:  https://scholar.google.com/citations?view_op=view_citation&hl=en&user=WwdhOCwAAAAJ&citation_for_view=WwdhOCwAAAAJ:RGFaLdJalmkC

The Evaluation of Poly(imide) Siloxane to use in Biomedical and Radiotherapy Applications

       JUNIPER PUBLISHERS-   ACADEMIC JOURNAL OF POLYMER SCIENCE Abstract Poly(imide) siloxane encourages new research studies that offer innovative and comprehensive industrial areas, experimental approaches and their innovative products. Poly(imide) siloxane covers the studies in fundamental organic polymer chemistry and physical organic chemistry, noval researches on membranes and interfaces. The possible applications of the poly(imide) siloxane as shielding material include facilities such as biological shielding at nuclear medicine departments. Keywords:  Copolymers; Poly(imide) siloxane; Radiation Introduction Polymer based drug gene delivery systems with critical structural features at the nanometere scale have attracted immense interest. Besides, polymer applications to drug/gen delivery has offered unprecedented opportunities for the creation of a variety of polymeric structures. The drugs including nanocarriers can be derived from poly(imide) silo...

Human-Centric Regulatory in Point-of-Care Manufacturing for 3D Printed PEEK Polymer Implants with Functionalized Implant Surface

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                                   JUNIPER PUBLISHERS-   ACADEMIC JOURNAL OF POLYMER SCIENCE Abstract This article aims to define a regulatory approach for future medical technologies to be applied to the research, design, development, and manufacturing of smart medical devices. In the scope of this perspective: A human-centric regulatory approach and regulatory thinking method for 3D printed PEEK polymer implants. Keywords:  POC solution; polymer; smart implant; regulatory thinking; human-centric regulatory; S.P.E.L.; surface functionalization; additive manufacturing Introduction The healthcare industry is in a transformative change: one of the key enablers of these changes is the proliferation of point-of-care (POC) technologies, which can improve clinical outcomes and reduce costs by increased access. POC technologies have the potential to improve the management and treatment of variou...

Modelling the Creep Curves of β-BOPP Film

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       JUNIPER PUBLISHERS-   ACADEMIC JOURNAL OF POLYMER SCIENCE Abstract The effect of annealing on the creep and recovery properties of β -BOPP film was studied. The creep resistance can be improved obviously by annealing, the modification becomes better with elongating the duration. Four-parameter Burger model and Weibull distribution function well described such cases. Keywords:  BOPP Film; Creep; Fitting; Burger Model; Weibull Distribution Function Introduction Biaxially oriented polypropylene (BOPP) film has become a widely used film material because of its light weight, good transparency, moisture-proof, non-toxic and simple preparation process. When the content of β crystal in BOPP is increased, the toughness and thermal deformation resistance of BOPP film is greatly improved such that its application scope is expanded. However, its internal structure will undergo such complex changes as the movement of chain segments, the unwinding of molecular cha...

Polymeric Materials for the Development of Dual↓Working Gastroretentive Drug Delivery Systems. A Breakthrough Approach

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   JUNIPER PUBLISHERS-   ACADEMIC JOURNAL OF POLYMER SCIENCE Abstract Oral route is the most convenient and widely used method of drug administration, representing about 90% of all therapies used. It displays great advantages, such as being non-invasive, easy to administer (with the consequent high patient compliance) and cost-effective. However, serious drawbacks to conventional oral dosage forms are imposed by the gastrointestinal tract. Large fluctuations in drug bioavailability are found due to the influence of physiological factors such as variations in pH, high enzymatic activity and gastric emptying. This is the reason why frequent drug administrations are required to maintain the therapeutic plasma level of the drug. Gastroretentive Drug Delivery Systems (GRDDS) have emerged as an ideal approach to overcome these drawbacks. They are designed to prolong the gastric residence time (GRT) of the dosage forms in the stomach so that the time between dose administration ...