Juniper Publishers: Virtuous Engineering is the Need of Hour: A Perspe...

Juniper Publishers: Virtuous Engineering is the Need of Hour: A Perspe...: Civil Engineering Research Journal Abstract The best quality of someone or something that creates something valuable can be con...

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Polymeric Materials for the Development of Dual↓Working Gastroretentive Drug Delivery Systems. A Breakthrough Approach

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   JUNIPER PUBLISHERS-   ACADEMIC JOURNAL OF POLYMER SCIENCE Abstract Oral route is the most convenient and widely used method of drug administration, representing about 90% of all therapies used. It displays great advantages, such as being non-invasive, easy to administer (with the consequent high patient compliance) and cost-effective. However, serious drawbacks to conventional oral dosage forms are imposed by the gastrointestinal tract. Large fluctuations in drug bioavailability are found due to the influence of physiological factors such as variations in pH, high enzymatic activity and gastric emptying. This is the reason why frequent drug administrations are required to maintain the therapeutic plasma level of the drug. Gastroretentive Drug Delivery Systems (GRDDS) have emerged as an ideal approach to overcome these drawbacks. They are designed to prolong the gastric residence time (GRT) of the dosage forms in the stomach so that the time between dose administration ...
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Authored by Ahmed Esmail Shalan                                                                            Opinion Advanced polymeric materials have showed considerable interest over the past few decades due to their tremendous advantageous coming from the combination of conventional polymeric materials and organic conductors [1-3]. Different features like mechanical, electrical, and optical properties can be founded for advanced polymers due to their confined dimensions at the nanoscale level. Advanced conductive polymers (ACPs) with synthetically tunable hierarchical 3D network structures consider to be one of the na...
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